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NCT05651334

Transcranial Magnetic Stimulation in Smokers: an Examination of Mediating Neural Pathways.

Kent State University·Phase 2·ClinicalTrials.gov·device·Device trialRecruiting
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Study focus
Disease/Condition
Smoking
Drug/Device/Intervention
Active repetitive Transcranial Magnetic Stimulation
Study type
Interventional
Intervention type
device
Sponsor & location
Primary sponsor
Kent State University
Location
Cleveland, United States of America
Timeline & enrollment
Phase
Phase 2
Start date
Nov 08, 2022
End date
May 30, 2024
Enrollment
16 participants
Primary outcome

Regulation of Craving Task,Brief Questionnaire of Smoking Urges (QSU - Brief)

Summary

The primary objective of this study is to examine the effects of repetitive transcranial
 magnetic stimulation (rTMS) on a regulation of craving task (ROC task) and evaluate the
 feasibility of targeting rTMS via fMRI based neuronavigation. Specifically, we will examine
 BOLD activation within the DLPFC when control over craving is exerted in order to identify if
 1) the task produces reliable activations in an area capable of being targeted by a standard
 figure-8 coil and 2) examine if the coordinates of the area are distinct from the area
 targeted via anatomical neuronavigation alone. Last, we will examine if rTMS, compared to
 sham, is capable of improving cognitive control over craving measured at outcome. The current
 pilot study will examine these aims in a sample of tobacco dependent adults (N=16) (with
 final sample size dependent on availability of funds).

ICD-10 classifications
Tobacco useExposure to tobacco smokeToxic effect: Tobacco and nicotineMental and behavioural disorders due to use of tobacco : harmful useDrug use
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT05651334
Type
Device Trial
About this record

Access comprehensive clinical trial information for NCT05651334 through Pure Global AI's free database. This Phase 2 trial is sponsored by Kent State University and is currently Recruiting. The study focuses on Smoking. Target enrollment is 16 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.