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NCT05940285Not yet recruiting

Dynamic 99mTc-Tetrofosmin CZT-SPECT Myocardial Perfusion Imaging in Comparison With Fractional Flow Reserve in Patients After ST-elevation Myocardial Infarction

Diagnostic Performances Assessment of Dynamic 99mTc- Tetrofosmin CZT-SPECT Myocardial Perfusion Imaging in Comparison With Invasive Intra-coronary Fractional Flow Reserve Measurement in Patients With Significant Residual Coronary Artery Stenosis After ST-elevation Myocardial Infarction : Dyna-MI Pilot Study.
Nantes University HospitalClinicalTrials.govdiagnostic test
Verified
Study focus
Disease/Condition
Myocardial Infarction
Drug/Device/Intervention
Dynamic 99mTc-Tetrofosmin CZT-SPECT
Study type
Interventional
Intervention type
diagnostic test
Sponsor & location
Primary sponsor
Nantes University Hospital
Location
Nantes, France
Timeline & enrollment
Phase
N/A
Start date
Sep 01, 2023
End date
Sep 01, 2026
Enrollment
60 participants
Primary outcome

Sensitivity, specificity, predictive positive value, negative predictive value, accuracy of MFR in comparison with FFR

Summary

Dynamic 99mTc-Tetrofosmin CZT-SPECT myocardial perfusion imaging (MPI) is an advanced
 functional imaging technique giving important myocardial flow quantification added data in
 comparison with conventional MPI, especially in coronary multi vessel disease. A large-scale
 validation of diagnostic performances of myocardial flow reserve (MFR) estimated with Dynamic
 99mTc-Tetrofosmin CZT-SPECT MPI would allow a non-invasive approach instead of invasive
 intra-coronary fractional flow reserve (FFR) measurement. The aim of this prospective study
 is to assess diagnostic performances of MFR calculated with dynamic 99mTc-Tetrofosmin
 CZT-SPECT MPI in comparison with invasive intra-coronary FFR measurement in patients with
 significant residual coronary arteries stenosis after ST-elevation myocardial infarction.

ICD-10 classifications
Acute myocardial infarctionAcute myocardial infarction, unspecifiedOld myocardial infarctionSubsequent myocardial infarctionObservation for suspected myocardial infarction
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT05940285
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT05940285 through Pure Global AI's free database. This phase not specified trial is sponsored by Nantes University Hospital and is currently Not yet recruiting. The study focuses on Myocardial Infarction. Target enrollment is 60 participants.

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