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NCT05959603Recruiting

Intra-wound Vancomycin Powder for Prevention of Surgical Site Infection Following Spinal Surgery

Intra-wound Vancomycin Powder for Prevention of Surgical Site Infection Following Spinal Surgery - a Randomized Controlled Superiority Trial
Rabin Medical CenterPhase 3ClinicalTrials.govdrug
Verified
Study focus
Disease/Condition
Infection
Drug/Device/Intervention
Vancomycin
Study type
Interventional
Intervention type
drug
Sponsor & location
Primary sponsor
Rabin Medical Center
Location
Petah tikva, Israel
Timeline & enrollment
Phase
Phase 3
Start date
May 31, 2020
End date
Dec 01, 2024
Enrollment
363 participants
Primary outcome

Incidence of deep spinal infections

Summary

Cefazolin is given routinely pre and intraoperatively for patients undergoing spinal surgery
 to reduce the rate of infection. Intra-wound admission of Vancomycin powder has been
 suggested to reduce wound infection rates. Therefore, this study aims to compare the rate of
 wound-related complications between patients receiving standard treatment compared to
 patients receiving an addition of topical Vancomycin and to identify the optimal Vancomycin
 dosage. All groups will receive the recommended regimen of routine IV antibiotic prophylaxis.

ICD-10 classifications
Bacterial infection, unspecifiedBacterial, viral and other infectious agentsInfection following immunizationOther infectious diseasesViral infection, unspecified
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT05959603
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT05959603 through Pure Global AI's free database. This Phase 3 trial is sponsored by Rabin Medical Center and is currently Recruiting. The study focuses on Infection. Target enrollment is 363 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.