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NCT06000280

Evaluation of Retina in Patients With Glaucoma Using Topical Prostaglandins Undergoing Trabeculectomy Surgery

Evaluation of Macular Thickness in Patients With Glaucoma in Use of Topical Prostaglandin Analogue Undergoing Trabeculectomy With Mitomycin C
Universidade Federal de Goias·ClinicalTrials.gov·procedureCompleted
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Study focus
Disease/Condition
Glaucoma
Drug/Device/Intervention
Trabeculectomy surgery
Study type
Interventional
Intervention type
procedure
Sponsor & location
Primary sponsor
Universidade Federal de Goias
Location
Goiânia, Brazil
Timeline & enrollment
Phase
N/A
Start date
Jan 04, 2021
End date
Mar 31, 2023
Enrollment
37 participants
Primary outcome

Previous use of prostaglandins does not change macular thickness after trabeculectomy

Summary

The aim of this study was to verify whether prostaglandin analogue (PA) eye drops influence
 the retinal thickness of glaucomatous patients undergoing trabeculectomy (TRAB) surgery. We
 selected eyes of patients with glaucoma with surgical indication for TRAB who were using PA
 eye drops and without previous retinal alterations, from the Centro de Referência em
 Oftalmologia (CEROF) from the Federal University of Goiás and Fundação Banco de Olhos de
 Goiás (FUBOG). Patients were divided into 2 groups: the study group (SG) and the control
 group (CG). In the CG, the PA was suspended between 30 and 60 days before the preoperative
 exams were performed (maximum of 15 days before surgery for both groups). All patients
 included were submitted to various eye exams before the procedure, and postoperatively on 3
 occasions: 1 to 3 days (PO1), 6 to 9 days (PO7) and 27 to 30 days (PO30) after surgery.

ICD-10 classifications
GlaucomaGlaucomaOther glaucomaGlaucoma, unspecifiedGlaucoma in diseases classified elsewhere
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06000280
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06000280 through Pure Global AI's free database. This phase not specified trial is sponsored by Universidade Federal de Goias and is currently Completed. The study focuses on Glaucoma. Target enrollment is 37 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.