Effect of Celery Seed on the Components of Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion

Waist Circumference (WC),Systolic Blood Pressure (SBP),Diastolic Blood Pressure (DBP),High-Density Lipoprotein (HDL-c),Fasting Blood Triglycerides Concentration (TG),Fasting Serum Glucose (FSG),Insulin Sensitivity (Matsuda Index),Total Insulin Secretion,First Phase of Insuline Secretion (Stumvoll Index)

The Metabolic Syndrome (MS) is a cluster of cardiometabolic risk factors, which include
 abdominal obesity, hyperglycemia, dyslipidemia, and high blood pressure. MS is a global
 health problem, it represents a risk factor for the progression of cardiovascular disease,
 entitie that constitute the main cause of mortality in the world and in Mexico. The current
 treatment involves lifestyle changes and pharmacological treatment for each of the components
 of MS, however, there is no single approved treatment to control all components. Celery seed
 (Apium graveolens L.) from the Apiaceae family contains the flavonoids apigenin and luteolin;
 essential oils such as d-limonene, selinene and phthalides such as 3-n-butylphthalide. Thanks
 to its bioactive components, celery seed has proven to be effective in treating individual MS
 disorders; however, most studies are in animal models and there are no clinical studies that
 evaluate its effectiveness on all components of the system. MS, insulin sensitivity and
 insulin secretion so it could appear as a new, safe and effective complementary therapy for
 the treatment of MS.
 
 The aim of this study is to evaluate the effect of celery seed on the components of metabolic
 syndrome, insulin sensitivity, and insulin secretion.