COMPARATIVE ANALYSIS OF THE MORPHO-MECHANICAL PROPERTIES OF RED BLOOD CELLS EXTRACTED FROM DIABETIC PATIENTS WITH AND WITHOUT MICROVASCULAR COMPLICATIONS
- Disease/Condition
- Diabetes Mellitus, Type 1
- Drug/Device/Intervention
- Blood test - atomic force microscopy in the force spectroscopy mode
- Study type
- Observational
- Intervention type
- diagnostic test
- Primary sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Phase
- N/A
- Start date
- Sep 29, 2023
- End date
- Sep 29, 2025
- Enrollment
- 48 participants
In 48 subjects with type 1 diabetes with and without microvascular complications, the average stiffness of red blood cells, measured using atomic force microscope and quantified using Young's modulus, will be measured.
The aim of the study is to analyse the biomechanical stiffness of red blood cells extracted
 from subjects with type I diabetes with and without microvascular complications through a
 biophysical characterization of red blood cells using microscopy, spectroscopy and scattering
 measurements. 48 subjects with type 1 diabetes, 24 with and 24 without microvascular
 complications will be enrolled. From all subjects a single blood sample will be taken to
 perform the analysis of red blood cells morpho-mechanical properties.
- Registry
- ClinicalTrials.gov
- Trial ID
- NCT06068205
- Type
- Non-Device Trial
Access comprehensive clinical trial information for NCT06068205 through Pure Global AI's free database. This phase not specified trial is sponsored by Fondazione Policlinico Universitario Agostino Gemelli IRCCS and is currently Not yet recruiting. The study focuses on Diabetes Mellitus, Type 1. Target enrollment is 48 participants.
This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.