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NCT06068504

Shear Stress in the Arteries of the Lower Limbs During Exercise in Patients With Peripheral Arterial Disease

Shear Stress in the Arteries of the Lower Limbs During Arm Cranking Exercise in Patients With Peripheral Arterial Disease
University of Nove de Julho·ClinicalTrials.gov·otherEnrolling by invitation
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Study focus
Disease/Condition
Peripheral Arterial Disease
Drug/Device/Intervention
Arm-cranking exercise
Study type
Interventional
Intervention type
other
Sponsor & location
Primary sponsor
University of Nove de Julho
Location
São Paulo, Brazil
Timeline & enrollment
Phase
N/A
Start date
Nov 01, 2023
End date
Dec 31, 2024
Enrollment
20 participants
Primary outcome

Femoral artery diameter [mm],Femoral artery shear rate [sec.-1],Femoral artery Blood flow [mL/min]

Summary

The aim of the study will be to evaluate shear stress and blood flow parameters in lower limb
 arteries during arm cycle ergometer exercise in participants with peripheral artery disease.
 Twenty patients participants with peripheral artery disease and claudication symptoms will be
 recruited. Participants will perform 3 experimental sessions in random order. Iarm-cranking
 (15 sets of two minutes exercise), warm water foot immersion, and control. During the
 interventions, blood pressure and heart rate will be assessed every 6 minutes. Measurements
 of arterial diameter, blood flow, anterograde and retrograde shear stress of the femoral
 artery will be evaluated using a two-dimensional ultrasound device with spectral Doppler.

ICD-10 classifications
Peripheral vascular disease, unspecifiedOther peripheral vascular diseasesOther specified peripheral vascular diseasesPeripheral angiopathy in diseases classified elsewhereOther congenital malformations of peripheral vascular system
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06068504
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06068504 through Pure Global AI's free database. This phase not specified trial is sponsored by University of Nove de Julho and is currently Enrolling by invitation. The study focuses on Peripheral Arterial Disease. Target enrollment is 20 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.