Examining Neurobiological Mechanisms Underlying the Therapeutic Effect of the Ketogenic Diet in Bipolar Disorder (BD)

Blood oxygen level-dependent (BOLD) signal at Scan 1,Blood oxygen level-dependent (BOLD) signal at Scan 2,Blood oxygen level-dependent (BOLD) signal at Scan 3,Manic symptoms at Scan 1,Manic symptoms at Scan 2,Manic symptoms at Scan 3,Fasting Glucose at Baseline,Fasting lipids at Baseline,Fasting hepatic function panel at Baseline: total protein,Fasting hepatic function panel at Baseline: albumin,Fasting hepatic function panel at Baseline: bilirubin,Fasting hepatic function panel at Baseline: liver enzyme,Fasting Glucose at halfway point through first dietary phase,Fasting lipids at halfway point through first dietary phase,Fasting hepatic function at halfway point through first dietary phase: total protein,Fasting hepatic function at halfway point through first dietary phase: albumin,Fasting hepatic function at halfway point through first dietary phase: bilirubin,Fasting hepatic function at halfway point through first dietary phase: liver enzyme,Fasting Glucose at end of first dietary phase,Fasting lipids at end of first dietary phase,Fasting hepatic function at end of first dietary phase: total protein,Fasting hepatic function at end of first dietary phase: albumin,Fasting hepatic function at end of first dietary phase: bilirubin,Fasting hepatic function at end of first dietary phase: liver enzyme,Fasting Glucose at halfway point through second dietary phase,Fasting lipids at halfway point through second dietary phase,Fasting hepatic function at halfway point through second dietary phase: total protein,Fasting hepatic function at halfway point through second dietary phase: albumin,Fasting hepatic function at halfway point through second dietary phase: bilirubin,Fasting hepatic function at halfway point through second dietary phase: liver enzyme,Fasting Glucose at end of second dietary phase,Fasting lipids at end of second dietary phase,Fasting hepatic function at end of second dietary phase: total protein,Fasting hepatic function at end of second dietary phase: albumin,Fasting hepatic function at end of second dietary phase: bilirubin,Fasting hepatic function at end of second dietary phase: liver enzyme,Gamma-aminobutyric acid (GABA) at Baseline,Glutamate at Baseline,Lactate at Baseline,Gamma-aminobutyric acid (GABA) at end of first dietary phase,Glutamate at end of first dietary phase,Lactate at end of first dietary phase,Gamma-aminobutyric acid (GABA) at end of second dietary phase,Glutamate at end of second dietary phase,Lactate at end of second dietary phase

The investigators aim to examine the effect of the ketogenic diet on brain activity,
 metabolism, and emotions in adults with Bipolar Disorder (BD).