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NCT06082999Recruiting

Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services

Gene-STEPS: Shortening Time of Evaluation in Paediatric Epilepsy Services: a Multi-centre Prospective Evaluation of the Impact of Early Genetic Diagnosis on Patient Outcomes
Great Ormond Street Hospital for Children NHS Foundation TrustClinicalTrials.gov
Verified
Study focus
Disease/Condition
Epilepsy
Study type
Observational
Sponsor & location
Primary sponsor
Great Ormond Street Hospital for Children NHS Foundation Trust
Location
Boston,Parkville,Toronto,London, Australia,Canada,United Kingdom,United States of America
Timeline & enrollment
Phase
N/A
Start date
Sep 01, 2021
End date
Dec 01, 2025
Enrollment
300 participants
Primary outcome

Feasibility of rapid genome sequencing in infantile epilepsy,The Diagnostic Yield of rapid genome sequencing in infantile epilepsy,The immediate clinical utility of rapid genome sequencing in infantile epilepsy

Summary

Overall, this observational cohort study aims too:
 
 1. Implement rapid trio WGS for all children presenting to our health systems with epilepsy
 onset under 12 months of age.
 
 2. Utilize electronic healthcare records and research databases to unite phenotypic and
 genomic data and to create a virtual registry across all institutions that will
 promote ongoing discovery.
 
 3. Assess the impact of early genetic diagnosis on epilepsy, developmental, and health
 economic outcomes through formal longitudinal assessments of all children enrolled.

ICD-10 classifications
EpilepsyEpilepsy, unspecifiedOther epilepsyStatus epilepticusOther status epilepticus
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06082999
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06082999 through Pure Global AI's free database. This phase not specified trial is sponsored by Great Ormond Street Hospital for Children NHS Foundation Trust and is currently Recruiting. The study focuses on Epilepsy. Target enrollment is 300 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.