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Ovary Syndrome for Efficient Diagnosis and Targeted Therapy - Trial NCT06102629

Access comprehensive clinical trial information for NCT06102629 through Pure Global AI's free database. This phase not specified trial is sponsored by Asian Institute of Gastroenterology, India and is currently Not yet recruiting. The study focuses on Polycystic Ovary Syndrome. Target enrollment is 200 participants.

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Trial Details
ClinicalTrials.gov โ€ข NCT06102629
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DJ Fang

DJ Fang

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Ovary Syndrome for Efficient Diagnosis and Targeted Therapy
Understanding the Epigenetic Mechanisms in the Pathophysiology of Polycystic Ovary Syndrome for Efficient Diagnosis and Targeted Therapy

Study Focus

Polycystic Ovary Syndrome

laparoscopy / laparotomy

Interventional

procedure

Sponsor & Location

Asian Institute of Gastroenterology, India

Hyderabad, India

Timeline & Enrollment

N/A

Nov 05, 2023

Nov 15, 2026

200 participants

Primary Outcome

Evaluate the Analysis of DNA methyl transferases,Evaluate the Analysis of differential mRNA and protein expression of epigenetic markers in ovarian tissues

Summary

OBJECTIVES:
 
 1. Analysis of DNA methyl transferases (DNMT1, DNMT3A and DNMT3B) and Histone deacetylases
 (HDAC 1,2,3 and SIRTs) polymorphisms (Somatic and germ line variations).
 
 2. Analysis of differential mRNA and protein expression of epigenetic markers in ovarian
 tissues obtained from PCOS patients.
 
 3. miRNA regulated epigenetic mechanisms in PCOS
 
 4. Epigenetic regulation of endocrine genes in PCOS
 
 DESIGN : A Case Control study.Sample size:200

ICD-10 Classifications

Polycystic ovarian syndrome
Ovarian dysfunction, unspecified
Ovarian dysfunction
Other ovarian dysfunction
Neoplasm of uncertain or unknown behaviour: Ovary

Data Source

ClinicalTrials.gov

NCT06102629

Non-Device Trial