NCT06102629

Ovary Syndrome for Efficient Diagnosis and Targeted Therapy

Name: Clinical Trial NCT06102629
Creator: Asian Institute of Gastroenterology, India
Keywords: Polycystic Ovary Syndrome, laparoscopy / laparotomy, procedure, clinical trial, India

Understanding the Epigenetic Mechanisms in the Pathophysiology of Polycystic Ovary Syndrome for Efficient Diagnosis and Targeted Therapy

Asian Institute of Gastroenterology, India·ClinicalTrials.gov·procedureNot yet recruiting

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Study focus

Disease/Condition: Polycystic Ovary Syndrome
Drug/Device/Intervention: laparoscopy / laparotomy
Study type: Interventional
Intervention type: procedure

Sponsor & location

Primary sponsor: Asian Institute of Gastroenterology, India
Location: Hyderabad, India

Timeline & enrollment

Phase: N/A
Start date: Nov 05, 2023
End date: Nov 15, 2026
Enrollment: 200 participants

Primary outcome

Evaluate the Analysis of DNA methyl transferases,Evaluate the Analysis of differential mRNA and protein expression of epigenetic markers in ovarian tissues

Summary

OBJECTIVES:  1. Analysis of DNA methyl transferases (DNMT1, DNMT3A and DNMT3B) and Histone deacetylases (HDAC 1,2,3 and SIRTs) polymorphisms (Somatic and germ line variations).  2. Analysis of differential mRNA and protein expression of epigenetic markers in ovarian tissues obtained from PCOS patients.  3. miRNA regulated epigenetic mechanisms in PCOS  4. Epigenetic regulation of endocrine genes in PCOS  DESIGN : A Case Control study.Sample size:200

ICD-10 classifications

Polycystic ovarian syndromeOvarian dysfunction, unspecifiedOvarian dysfunctionOther ovarian dysfunctionNeoplasm of uncertain or unknown behaviour: Ovary

Data source

Registry: ClinicalTrials.gov
Trial ID: NCT06102629
Type: Non-Device Trial

About this record

Access comprehensive clinical trial information for NCT06102629 through Pure Global AI's free database. This phase not specified trial is sponsored by Asian Institute of Gastroenterology, India and is currently Not yet recruiting. The study focuses on Polycystic Ovary Syndrome. Target enrollment is 200 participants.

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