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NCT06105125

Autologous Micrografts From the Palatal Mucosa for Periodontal Regeneration

Periodontal Regeneration in Non-contained Intrabony Defects Using Autologous Micrografts From the Palatal Mucosa: a Randomized Controlled Clinical Trial
University of Turin, Italy·ClinicalTrials.gov·device·Device trialRecruiting
View on ClinicalTrials.gov →
Study focus
Disease/Condition
Periodontitis
Drug/Device/Intervention
Rigenera + bone substitute
Study type
Interventional
Intervention type
device
Sponsor & location
Primary sponsor
University of Turin, Italy
Location
Turin, Italy
Timeline & enrollment
Phase
N/A
Start date
Nov 02, 2023
End date
Nov 02, 2025
Enrollment
38 participants
Primary outcome

Clinical attachment level change

Summary

Some research studies have demonstrated that autologous micrografts made out of different
 oral tissues may enhance tissue regeneration. The primary aim of this study is to evaluate
 the clinical performance of a combined approach using an autologous micrograft derived from
 the palatal mucosa with an alloplastic scaffold for periodontal regeneration of intrabony
 defects in terms of clinical attachment level gain (primary outcome) and other secondary
 outcomes (probing pocket depth reduction, radiographic bone fill) compared to a scaffold
 alone. Moreover, this study aims to compare early wound healing and patient-reported outcome
 measures between the two groups.

ICD-10 classifications
Chronic periodontitisPeriodontosisAcute periodontitisChronic apical periodontitisPeriodontal disease, unspecified
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06105125
Type
Device Trial
About this record

Access comprehensive clinical trial information for NCT06105125 through Pure Global AI's free database. This phase not specified trial is sponsored by University of Turin, Italy and is currently Recruiting. The study focuses on Periodontitis. Target enrollment is 38 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.