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NCT06106776Not yet recruiting

CAR-T Cell Induced Cardiac Dysfunction: A Prospective Study

PROSPECTIVE OBSERVATIONAL STUDY FOR THE ASSESSMENT OF CARDIAC DYSFUNCTION INDUCED BY CHIMERIC ANTIGEN RECEPTOR T (CAR-T) CELL THERAPY
Fondazione Policlinico Universitario Agostino Gemelli IRCCSClinicalTrials.govdrug
Study focus
Disease/Condition
Lymphoma
Drug/Device/Intervention
Chimeric Antigen Receptor
Study type
Observational
Intervention type
drug
Sponsor & location
Primary sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Timeline & enrollment
Phase
N/A
Start date
Nov 02, 2023
End date
Jan 31, 2026
Enrollment
48 participants
Primary outcome

Incidence of Cancer Therapy Related Cardiac Dysfunction

Summary

In this observational, prospective study, patients affected by B-cell Lymphoma and candidate
 to chimeric antigen receptor-T (CAR-T) cell infusion will be evaluated at three timepoints to
 establish the rate of cardiac dysfunction, defined according to 2022 European Society of
 Cardiology Cardio-Oncology guidelines. Echocardiography, physical examination and
 cardiac/inflammatory biomarkers will be performed prior to CAR-T cell infusion and followed
 at 7 days and 1 month.

ICD-10 classifications
Hodgkin lymphomaFollicular lymphomaNon-Hodgkin lymphoma, unspecifiedFollicular lymphoma, unspecifiedHodgkin lymphoma, unspecified
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06106776
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06106776 through Pure Global AI's free database. This phase not specified trial is sponsored by Fondazione Policlinico Universitario Agostino Gemelli IRCCS and is currently Not yet recruiting. The study focuses on Lymphoma. Target enrollment is 48 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.