Toxicity and Efficacy Evaluation of Topical Minoxidil in Acne Vulgaris

Change from baseline systolic blood pressure

Patients with acne vulgaris (AV) appeared to be a chronic inflammation with a wide range in
 teenagers and adult. The protocol design is as follows.
 
 The subjects enrolled through inclusion and exclusion criteria will undergo the blood and
 urine biochemical tests for baseline record. The photos from the subjects will be recorded
 per day, and the blood and urine biochemical tests will be recorded per week.
 
 Objectives: primary: to test the toxicity of topical minoxidil in treatment of acne vulgaris;
 second: to evaluate the response and disease control rate in this pilot study.
 
 Measurement: Time to resolution of individual acne lesions (14 days) Monitor of treatment
 efficacy: number of inflammatory acne lesions counting, time to resolution of individual acne
 lesion, and degree of acne severity measurement.