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NCT06133790Not yet recruiting

Profiles of Expression in HPV+ Versus HPV Head and Neck Cancers

Assessment of Genomic Alterations and Profiles of Expression in HPV+ Versus HPV Head and Neck Cancers
GCS Ramsay Santé pour l'Enseignement et la RechercheClinicalTrials.govgenetic
Verified
Study focus
Disease/Condition
Head and Neck Cancer
Drug/Device/Intervention
PCR - Immunohistochemistry - Immunolabelling
Study type
Observational
Intervention type
genetic
Sponsor & location
Primary sponsor
GCS Ramsay Santé pour l'Enseignement et la Recherche
Timeline & enrollment
Phase
N/A
Start date
Jan 01, 2024
End date
Jun 30, 2024
Enrollment
60 participants
Primary outcome

Molecular profile of oropharyngeal or oral cavity HPV positive and negative tumors

Summary

Squamous cell cancers of the head and neck are classically correlated to excessive
 consumption of alcohol and tobacco and have a rather poor prognosis. However, the incidence
 of Head and Neck cancers in patients without alcohol-smoking risk factor has continued to
 increase in recent years, in relation to more and more frequent HPV contamination.
 
 Some studies show a difference in the expression of certain genes within the two groups of
 tumors (HPV+ and HPV-) including some that confer sensitivity to certain chemotherapies and
 others to radiotherapy. However, patients with HPV+ Head and Neck cancers are treated
 according to the same referential as HPV- Head and Neck cancers. There is therefore a real
 need for studies identifying predictive markers in order to be able to offer patients a more
 effective suitable and less invasive treatment.

ICD-10 classifications
Malignant neoplasm of other and ill-defined sites: Head, face and neckMalignant neoplasm: Skin of scalp and neckMalignant neoplasm: Connective and soft tissue of head, face and neckCarcinoma in situ: Skin of scalp and neckSecondary and unspecified malignant neoplasm: Lymph nodes of head, face and neck
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06133790
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06133790 through Pure Global AI's free database. This phase not specified trial is sponsored by GCS Ramsay Santé pour l'Enseignement et la Recherche and is currently Not yet recruiting. The study focuses on Head and Neck Cancer. Target enrollment is 60 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.