Profiles of Expression in HPV+ Versus HPV Head and Neck Cancers - Trial NCT06133790
Access comprehensive clinical trial information for NCT06133790 through Pure Global AI's free database. This phase not specified trial is sponsored by GCS Ramsay Santé pour l'Enseignement et la Recherche and is currently Not yet recruiting. The study focuses on Head and Neck Cancer. Target enrollment is 60 participants.
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Study Focus
Sponsor & Location
GCS Ramsay Santé pour l'Enseignement et la Recherche
Timeline & Enrollment
N/A
Jan 01, 2024
Jun 30, 2024
Primary Outcome
Molecular profile of oropharyngeal or oral cavity HPV positive and negative tumors
Summary
Squamous cell cancers of the head and neck are classically correlated to excessive
 consumption of alcohol and tobacco and have a rather poor prognosis. However, the incidence
 of Head and Neck cancers in patients without alcohol-smoking risk factor has continued to
 increase in recent years, in relation to more and more frequent HPV contamination.
 
 Some studies show a difference in the expression of certain genes within the two groups of
 tumors (HPV+ and HPV-) including some that confer sensitivity to certain chemotherapies and
 others to radiotherapy. However, patients with HPV+ Head and Neck cancers are treated
 according to the same referential as HPV- Head and Neck cancers. There is therefore a real
 need for studies identifying predictive markers in order to be able to offer patients a more
 effective suitable and less invasive treatment.
ICD-10 Classifications
Data Source
ClinicalTrials.gov
NCT06133790
Non-Device Trial