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NCT06140576Not yet recruiting

The Efficacy and Safety of Lenvatinib Combined With Sindilimab and Nab-paclitaxel in the First-line Treatment for Recurrent and Metastatic Triple Negative Breast Cancer: a Phase Ib/IIa Clinical Trial.

Zhejiang Cancer HospitalPhase 1/2ClinicalTrials.govdrug
Study focus
Disease/Condition
Breast Neoplasms
Drug/Device/Intervention
Sindilimab
Study type
Interventional
Intervention type
drug
Sponsor & location
Primary sponsor
Zhejiang Cancer Hospital
Location
Hangzhou, China
Timeline & enrollment
Phase
Phase 1/2
Start date
Nov 30, 2023
End date
Dec 31, 2026
Enrollment
58 participants
Primary outcome

safety and tolerability,Objective Response Rate (ORR)

Summary

The treatment regimen of lenvatinib combined with PD1 antibody has brought earth shaking
 changes to the immunotherapy of various cold tumors. This is a phase Ib/IIa clinical trial
 to investigate the efficacy and safety of Lenvatinib combined with Sindilimab and
 Nab-paclitaxel in the first-line treatment for recurrent and metastatic triple negative
 breast cancer.

ICD-10 classifications
Malignant neoplasm of breastMalignant neoplasm of breastMalignant neoplasm: Breast, unspecifiedBenign neoplasm of breastMalignant neoplasm: Central portion of breast
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06140576
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06140576 through Pure Global AI's free database. This Phase 1/2 trial is sponsored by Zhejiang Cancer Hospital and is currently Not yet recruiting. The study focuses on Breast Neoplasms. Target enrollment is 58 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.