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NCT06152003

Intervention Development for Syndemics Among PWH in SA

Developing and Piloting a Multilevel Intervention to Address Psychosocial and Structural Syndemics in People With HIV in South Africa
Massachusetts General Hospital·ClinicalTrials.gov·behavioralNot yet recruiting
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Study focus
Disease/Condition
HIV Infections
Drug/Device/Intervention
Cognitive Behavioral Therapy for Syndemics and Adherence (CBT-SA)
Study type
Interventional
Intervention type
behavioral
Sponsor & location
Primary sponsor
Massachusetts General Hospital
Timeline & enrollment
Phase
N/A
Start date
May 01, 2024
End date
Jun 01, 2028
Enrollment
60 participants
Primary outcome

75% of participants randomized to CBT-SA attend at least 66% of the sessions,75% of the participants randomized to CBT-SA attend the 6-month follow-up visit.

Summary

In South Africa, the country with the highest HIV prevalence (19%), co-occurring problems
 such as depression, post-traumatic stress, and food insecurity interact to enhance one
 another (i.e., syndemic problems) and are associated with worse HIV outcomes such as worse
 antiretroviral therapy (ART) adherence and worse viral load. This study proposes to: 1)
 explore how syndemic problems work together to make health worse for people with HIV (PWH)
 and explore what people think about a potential treatment; 2) develop a treatment to address
 syndemic problems and improve ART adherence (CBT-SA); 3a) assess whether people are willing
 to receive the CBT-SA we it can actually be done; and 3b) identify factors that make it
 easier or more difficult to receive CBT-SA.

ICD-10 classifications
HIV disease resulting in other viral infectionsHIV disease resulting in other bacterial infectionsHIV disease resulting in multiple infectionsAcute HIV infection syndromeHIV disease resulting in other infectious and parasitic diseases
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06152003
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06152003 through Pure Global AI's free database. This phase not specified trial is sponsored by Massachusetts General Hospital and is currently Not yet recruiting. The study focuses on HIV Infections. Target enrollment is 60 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.