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NCT06153706

Evaluation of L-PRF as an Antibiotic Slow-release Biological Device in the Treatment of Moderate Periodontitis

Evaluation of L-PRF as an Antibiotic Slow-release Biological Device in the Treatment of Moderate Periodontitis (A Randomized Controlled Clinical Trial)
Yasmeen Khaled·Phase 2/3·ClinicalTrials.gov·drugCompleted
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Study focus
Disease/Condition
Periodontitis
Drug/Device/Intervention
Subgingival application of L-PRF loaded with metronidazole
Study type
Interventional
Intervention type
drug
Sponsor & location
Primary sponsor
Yasmeen Khaled
Funder
Alexandria University
Location
Alexandria, Egypt
Timeline & enrollment
Phase
Phase 2/3
Start date
Jun 01, 2022
End date
Oct 01, 2023
Enrollment
24 participants
Primary outcome

Plaque accumulation,Gingival inflammation,Bleeding on probing,Probing depth,Clinical attachment loss,Quantitative assessment of Porhyromonas gingivalis

Summary

This study aimed to evaluate the efficacy of leukocyte platelet-rich fibrin (L-PRF) as a
 local sustained released device for antibiotics.

ICD-10 classifications
Chronic periodontitisPeriodontosisAcute periodontitisChronic apical periodontitisPeriodontal disease, unspecified
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06153706
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06153706 through Pure Global AI's free database. This Phase 2/3 trial is sponsored by Yasmeen Khaled and is currently Completed. The study focuses on Periodontitis. Target enrollment is 24 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.