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NCT06206629Recruiting

Contralateral R1 in Amyotrophic Lateral Sclerosis

Evaluation of Contralateral R1 Component of the Blink Reflex in Patients With Amyotrophic Lateral Sclerosis
Hospices Civils de LyonClinicalTrials.govdiagnostic test
Study focus
Drug/Device/Intervention
blink reflex evaluation
Study type
Observational
Intervention type
diagnostic test
Sponsor & location
Primary sponsor
Hospices Civils de Lyon
Location
Bron,Nantes, France
Timeline & enrollment
Phase
N/A
Start date
Feb 15, 2024
End date
Feb 15, 2025
Enrollment
120 participants
Primary outcome

Presence of a contralateral R1 component on blink reflex evaluation.

Summary

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting both upper and
 lower motor neurons. Electroneuromyography is an important tool for the diagnosis. Previous
 studies have shown that different components of the blink reflex, such as the latencies of
 homo- and contralateral R2 responses can be affected. Studies have found that a contralateral
 R1 component can appear in neurological diseases with affection of the central nervous system
 especially upper motor neuron, such as HTLV1 infection. Thus, you aim to determine if a
 contralateral R1 component could be present in ALS.

ICD-10 classifications
Neuralgic amyotrophyMotor neuron diseaseOther degenerative diseases of the nervous systemOther degenerative disorders of nervous system in diseases classified elsewhereMultiple sclerosis
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06206629
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06206629 through Pure Global AI's free database. This phase not specified trial is sponsored by Hospices Civils de Lyon and is currently Recruiting. The study focuses on Amyotrophic Lateral Sclerosis. Target enrollment is 120 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.