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NCT06247462

Ibuprofen and Biomarkers of Acute Kidney Injury After Running in the Heat

University of New Mexico·Phase 1·ClinicalTrials.gov·drugCompleted
View on ClinicalTrials.gov →
Study focus
Disease/Condition
Acute Kidney Injury
Drug/Device/Intervention
Ibuprofen 600 mg
Study type
Interventional
Intervention type
drug
Sponsor & location
Primary sponsor
University of New Mexico
Location
Albuquerque, United States of America
Timeline & enrollment
Phase
Phase 1
Start date
Jun 01, 2023
End date
Sep 05, 2023
Enrollment
12 participants
Primary outcome

Biomarkers of Acute Kidney Injury from Ibuprofen Ingestion Prior to Exercise in the Heat

Summary

The goal of this study is to determine if ibuprofen prior to exercise in the heat worsens
 biomarkers of acute kidney injury. Participants were given 600mg of ibuprofen or placebo
 (corn starch) 12- and 1-hour prior to running for 1-hour in a hot environment (35°C) at
 moderate intensity. Urine, plasma, and serum samples were collected pre-, post-, and 1hour
 post-exercise to assess biomarkers of acute kidney injury. This was a double blind,
 randomized crossover design, so that participants completed the alternate trial (ibuprofen or
 placebo) at least seven days later.

ICD-10 classifications
Injury of kidneyAcute renal failureAcute renal failure, unspecifiedOther acute renal failureAcute renal failure with tubular necrosis
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06247462
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06247462 through Pure Global AI's free database. This Phase 1 trial is sponsored by University of New Mexico and is currently Completed. The study focuses on Acute Kidney Injury. Target enrollment is 12 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.