NCT06282848

Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate

Pharmacological (0.05% Atropine) and Non-pharmacological (Defocused Incorporated Multiple Segments Lens) Treatment Effects on the Children With Different Predicted Myopia Progression Rate Measured by Modified Multifocal Electroretinogram
The Hong Kong Polytechnic University·ClinicalTrials.gov·drugRecruiting
View on ClinicalTrials.gov
Study focus
Disease/Condition
Myopia
Drug/Device/Intervention
Atropine 0.05%
Study type
Interventional
Intervention type
drug
Sponsor & location
Primary sponsor
The Hong Kong Polytechnic University
Location
Hong Kong, China
Timeline & enrollment
Phase
N/A
Start date
Jan 01, 2024
End date
Dec 01, 2026
Enrollment
80 participants
Primary outcome

Subjective refraction,Axial length

Summary

The goal of this clinical trial is to compare pharmacological and non-pharmacological
 treatment effects on the children with different predicted myopia progression rate measured
 by modified multifocal electroretinogram. The main questions it aims to answer are:
 
 - the effectiveness of using 0.05% atropine and prescribing DIMS lens for myopia control
 in children with different myopia progression rates
 
 - the contribution of L/M cones in juvenile myopia progression and changes of retinal
 activities under atropine and DIMS treatment.
 
 Participants will have baseline and follow-up eye examinations and given either
 pharmacological treatment with 0.05% atropine or non-pharmacological treatment with DIMS lens
 for myopia control.
 
 Researchers will compare the changes of refractive errors and axial length after different
 types of interventions and investigate the relations between the parameters of mfERG
 responses and the thicknesses of retinal layers and choroid.

ICD-10 classifications
MyopiaDegenerative myopiaAmblyopia ex anopsiaOcular myiasisMyiasis
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06282848
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06282848 through Pure Global AI's free database. This phase not specified trial is sponsored by The Hong Kong Polytechnic University and is currently Recruiting. The study focuses on Myopia. Target enrollment is 80 participants.

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