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NCT06301893Recruiting

Uganda Sickle Surveillance Study (US-3)

Prevalence and Mapping of Sickle Cell Trait and Disease in Uganda
Children's Hospital Medical Center, CincinnatiClinicalTrials.gov
Verified
Study focus
Disease/Condition
Sickle Cell Disease
Study type
Observational
Sponsor & location
Primary sponsor
Children's Hospital Medical Center, Cincinnati
Location
Kampala,Kampala,Kampala,Kampala, Uganda
Timeline & enrollment
Phase
N/A
Start date
Sep 07, 2013
End date
Dec 31, 2032
Enrollment
1000000 participants
Primary outcome

Incidence of HbSS and HbA

Summary

It is estimated that over 250,000 babies are born with sickle cell disease (SCD) annually in
 sub-Saharan Africa, and only 10% - 50% of them survive beyond five years of age. Data
 describing the magnitude of the sickle cell problem are lacking in most African countries.
 The available data on prevalence were mainly from older studies and small numbers of
 hospitalized patients. In Uganda, approximately 25,000 children are born with SCD but 70-80%
 die before their 5th birthday. Lehmann and Raper found 'sicklaemia' prevalence of 0.8% and
 45% in the Sebei and Bambaa ethnic groups, respectively. A recent study found a SCT and SCD
 prevalence of 3% - 19% and 0% - 3%, respectively but this study addressed only 5 of Uganda's
 111 districts and used a small convenience sample of children aged 6 - 60 months. The
 objective of this study is to determine the prevalence and map out the burden of SCT and SCD
 in Uganda.

ICD-10 classifications
Sickle-cell disordersOther sickle-cell disordersSickle-cell traitSickle-cell anaemia with crisisSickle-cell anaemia without crisis
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06301893
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06301893 through Pure Global AI's free database. This phase not specified trial is sponsored by Children's Hospital Medical Center, Cincinnati and is currently Recruiting. The study focuses on Sickle Cell Disease. Target enrollment is 1000000 participants.

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