Efficacy of Photodynamic Therapy and LASER Disinfection in Periodontal Therapy for Treatment of Periodontitis

Probing Pocket Depth (PPD)

The goal of this clinical trial is to Investigate the clinical and microbiological efficacies
 of Laser disinfection and ICG-mediated aPDT as adjunct to RSD for patients with
 periodontitis. The main question it aims to answer is:
 
 Does the use of laser disinfection or ICG-mediated aPDT as adjunct to RSD are effective in
 improving clinical parameters and reducing the load of periodontal pathogens.
 
 Participants will undergo full-mouth supragingival debridement by using ultrasonic device at
 baseline.
 
 All patients will be instructed to brush their teeth twice daily and will be supplied with
 the same type of tooth paste and toothbrush, with suitable interdental aids.
 
 All the patients will be instructed to attend again after 7 days. One week later, sites
 randomly allocated to control (Ctrl) group and test groups which will receive, in addition to
 RSD, either aPDT or periodontal pocket disinfection (Biolase). For all groups, sites with
 initial PPD 4-6 mm will be treated with RSD using area specific (Graecy) curettes.