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NCT06311045

Obstructive Sleep Apnea (OSA) and Sex-Specific Responses to N-acetylcysteine (NAC)

Basis of Sex-specific Therapeutic Responses to Obstructive Sleep Apnea (OSA): a Trial of N-acetylcysteine (NAC) in Obstructive Sleep Apnea (OSA)
NYU Langone Health·ClinicalTrials.gov·dietary supplementNot yet recruiting
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Study focus
Disease/Condition
Obstructive Sleep Apnea
Drug/Device/Intervention
N-acetylcysteine (NAC)
Study type
Interventional
Intervention type
dietary supplement
Sponsor & location
Primary sponsor
NYU Langone Health
Location
New York, United States of America
Timeline & enrollment
Phase
N/A
Start date
Apr 01, 2024
End date
Dec 01, 2028
Enrollment
206 participants
Primary outcome

Percent Change in Overnight Levels of Glutathione (GSH),Mean Change in Pre- to Post-Sleep GSH Levels,Mean Change in Pre- to Post-Sleep GSH Levels

Summary

This is a randomized controlled trial (RCT) of 4 weeks of study supplement N-acetylcysteine
 (NAC) versus placebo in persons with significant obstructive sleep apnea (OSA) who are
 receiving positive airway pressure therapy (PAP), the standard of care therapy. The purpose
 of the study is to determine if NAC is associated with sex-specific changes in overnight
 oxidative stress, inflammation, as well as endothelial dysfunction in persons with OSA.

ICD-10 classifications
Sleep apnoeaSleep disordersSleep disorder, unspecifiedPrimary sleep apnoea of newbornNonorganic sleep disorders
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06311045
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06311045 through Pure Global AI's free database. This phase not specified trial is sponsored by NYU Langone Health and is currently Not yet recruiting. The study focuses on Obstructive Sleep Apnea. Target enrollment is 206 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.