NCT06318923

Social and Moral Cognition in Multiple Sclerosis

Lille Catholic University·ClinicalTrials.gov·otherRecruiting
View on ClinicalTrials.gov
Study focus
Disease/Condition
Multiple Sclerosis
Drug/Device/Intervention
Socio-demographic questionnaire, moral judgment task, cognitive tests, psychoaffective assessment
Study type
Interventional
Intervention type
other
Sponsor & location
Primary sponsor
Lille Catholic University
Location
Lille,Lomme, France
Timeline & enrollment
Phase
N/A
Start date
Dec 19, 2023
End date
Oct 30, 2025
Enrollment
90 participants
Primary outcome

Moral dilemma judgments

Summary

Multiple Sclerosis (MS) is a chronic, progressive disease that affects young adults (aged
 between 20 and 40) and has a major impact on patients' quality of life. Cognitive disorders
 in MS are common, affecting 40-60% of patients. Among these disorders, the presence of social
 cognition disorders is common. Within social cognition, the moral judgment has been an object
 of research in order to understand the determinants of moral decision-making: how and why
 individuals make moral choices with regard to a set of prescriptions and social norms.
 Compared to control subjects, MS patients show a decrease in moral permissiveness, as well as
 an increase in moral relativity and emotional reactivity. Thus, it would seem that MS
 patients issue more deontological choices (lower moral permissiveness). Given that these
 patients also exhibit empathy deficits and higher alexithymia, these patterns are surprising.
 Indeed, in other clinical populations, low empathic abilities and high alexithymia are linked
 to utilitarian rather than deontological moral judgments.
 
 The objective of this project is to analyze the process of decision-making carried out by
 patients during moral dilemma situations in comparison with control individuals and verify
 whether the presence of a positivity bias could explain the more deontological choices made
 by some patients. Indeed, some work has shown that older individuals make more deontological
 moral judgments than younger adults. These results are also observed with young individuals
 when their future temporal perspectives have been experimentally constrained.

ICD-10 classifications
Multiple sclerosisProgressive systemic sclerosisSystemic sclerosisSystemic sclerosis, unspecifiedDiffuse sclerosis
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06318923
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06318923 through Pure Global AI's free database. This phase not specified trial is sponsored by Lille Catholic University and is currently Recruiting. The study focuses on Multiple Sclerosis. Target enrollment is 90 participants.

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