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NCT06323161Recruiting

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Once-daily Basal Insulin With or Without Metformin

Efficacy and Safety of Co-administered Cagrilintide and Semaglutide (CagriSema) s.c. in Doses 2.4 mg/2.4 mg and 1.0 mg/1.0 mg Once Weekly Versus Placebo in Participants With Type 2 Diabetes as Add on to Once-daily Basal Insulin With or Without Metformin
Novo Nordisk A/SPhase 3ClinicalTrials.govdrug
Study focus
Disease/Condition
Type 2 Diabetes
Drug/Device/Intervention
Cagrilintide
Study type
Interventional
Intervention type
drug
Sponsor & location
Primary sponsor
Novo Nordisk A/S
Location
Northridge,Miami,Meridian,West Des Moines,Newton,Flint,Las Vegas,Chapel Hill,Nashville,Dallas,Houston,Houston,Manassas,Newport News,Beijing,Nanjing,Zhenjiang,Ji'nan,Shanghai,Sapporo-shi, Hokkaido,Yama, China,Japan,Serbia,Slovakia,South Africa,United States of America
Timeline & enrollment
Phase
Phase 3
Start date
Mar 26, 2024
End date
Nov 04, 2025
Enrollment
270 participants
Primary outcome

Change in Glycated Haemoglobin (HbA1c)

Summary

This study will look at how much CagriSema helps people with type 2 diabetes lower their
 blood sugar and body weight. CagriSema is a new investigational medicine. Doctors may not yet
 prescribe CagriSema. CagriSema will be compared to a dummy medicine (also called placebo)
 that has no effect on the body. Participant will get either CagriSema or dummy medicine and
 which treatment they get is decided by chance. Participant will take the study medicine
 together with their current diabetes medicine (once-daily insulin with or without metformin).
 For each participant, the study will last for about one year.

ICD-10 classifications
Type 2 diabetes mellitusType 2 diabetes mellitus without complicationsType 2 diabetes mellitus with unspecified complicationsType 2 diabetes mellitus with other specified complicationsType 2 diabetes mellitus with multiple complications
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06323161
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06323161 through Pure Global AI's free database. This Phase 3 trial is sponsored by Novo Nordisk A/S and is currently Recruiting. The study focuses on Type 2 Diabetes. Target enrollment is 270 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.