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NCT06329518

Rezafungin PK in Patients on ECMO

Pharmacokinetics and Ex Vivo Sequestration of Rezafungin in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation (ECMO)
Hartford Hospital·Phase 1·ClinicalTrials.gov·drugNot yet recruiting
View on ClinicalTrials.gov →
Study focus
Disease/Condition
Sepsis
Drug/Device/Intervention
Rezafungin
Study type
Interventional
Intervention type
drug
Sponsor & location
Primary sponsor
Hartford Hospital
Location
Hartford, United States of America
Timeline & enrollment
Phase
Phase 1
Start date
Apr 01, 2024
End date
Apr 01, 2025
Enrollment
8 participants
Primary outcome

Rezafungin Clearance

Summary

Extracorporeal membrane oxygenation (ECMO) is a form of cardiopulmonary life-support for
 critically ill patients where blood is extracted from the vascular system and circulated by a
 mechanical pump while it is oxygenated and reinfused into the patient's circulation. It is
 well known that critically ill patients may experience alterations in antibiotic
 pharmacokinetics, and as a result, dosing modifications are generally required. There is a
 need to understand how ECMO circuits affect the pharmacokinetics and disposition of drugs.
 This study is designed to assess the pharmacokinetics of the new broad-spectrum echinocandin,
 Rezafungin, in critically ill patients receiving ECMO

ICD-10 classifications
Other sepsisSepsis, unspecifiedOther specified sepsisCandidal sepsisPuerperal sepsis
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06329518
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06329518 through Pure Global AI's free database. This Phase 1 trial is sponsored by Hartford Hospital and is currently Not yet recruiting. The study focuses on Sepsis. Target enrollment is 8 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.