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NCT06334575Not yet recruiting

Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels

Maria Joyera RodríguezPhase 4ClinicalTrials.govdrug
Study focus
Drug/Device/Intervention
Budesonide
Study type
Interventional
Intervention type
drug
Sponsor & location
Primary sponsor
Maria Joyera Rodríguez
Funder
Fundacion Clinic per a la Recerca Biomédica
Location
Marburg,Groningen,Barcelona,Palma De Mallorca,Leicester,London, Germany,Netherlands,Spain,United Kingdom
Timeline & enrollment
Phase
Phase 4
Start date
Jul 01, 2024
End date
Dec 01, 2025
Enrollment
135 participants
Primary outcome

Significant molecular changes in COPD stratified by their blood eosinophil counts.

Summary

The 3TR-ICS COPD study is an international, multicentre, randomized, parallel, controlled
 study that will recruit clinically stable former smokers COPD patients (with no exacerbations
 in the previous 8 weeks) on treatment with dual long-acting bronchodilators (LABA+LAMA),
 minimum 8 weeks of usage, not receiving ICS (either naïve or 3 months since last usage).
 The overall objective of this clinical trial is to identify the molecular signatures
 associated with the molecular response to ICS treatment in patients with COPD stratified by
 the levels of circulating eosinophils, and the potential influence of the pulmonary
 microbiome

ICD-10 classifications
Other chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease, unspecifiedOther specified chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease with acute exacerbation, unspecifiedChronic obstructive pulmonary disease with acute lower respiratory infection
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06334575
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06334575 through Pure Global AI's free database. This Phase 4 trial is sponsored by Maria Joyera Rodríguez and is currently Not yet recruiting. The study focuses on Chronic Obstructive Pulmonary Disease. Target enrollment is 135 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.