Short-term and Long-term Outcomes of Colorectal Cancer Treated With Natural Orifice Specimen Extraction Surgery : a National Registry-based Study

Rate of short-term complication

Natural orifice specimen extraction surgery (NOSES) has gained widespread recognition among
 scholars and has gradually been promoted and popularized around the world. However, the
 development of NOSES is still in the exploratory stage and there is a lack of strong evidence
 from evidence-based medicine to support its feasibility and safety, which has greatly
 affected its clinical application and development. Based on this, at the call of Professor
 Xishan Wang, the Chinese NOSES Alliance conducted a large retrospective clinical study
 involving multiple centers. By summarizing the NOSES cases of nearly 100 centers in China,
 the study aims to clarify the current status of NOSES surgery in China. Additionally, a
 comprehensive analysis and summary was conducted by combining the basic information of NOSES
 patients, perioperative data, postoperative pathological data, and follow-up information to
 further demonstrate the safety and feasibility of NOSES in the treatment of colorectal
 cancer. This study also provides more real and objective evidence-based medicine support for
 the promotion and development of NOSES surgery.