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NCT06362642

A Study to Investigate the Effects of Itraconazole on the Pharmacokinetics of PC14586 in Healthy Participants

A Phase 1, Open-label, Fixed-sequence Study to Investigate the Effect of Coadministration of Itraconazole on the Pharmacokinetics of PC14586 in Healthy Participants
PMV Pharmaceuticals, Inc·Phase 1·ClinicalTrials.gov·drugRecruiting
View on ClinicalTrials.gov →
Study focus
Disease/Condition
Healthy Volunteers
Drug/Device/Intervention
PC14586
Study type
Interventional
Intervention type
drug
Sponsor & location
Primary sponsor
PMV Pharmaceuticals, Inc
Location
Madison, United States of America
Timeline & enrollment
Phase
Phase 1
Start date
Mar 28, 2024
End date
Dec 01, 2024
Enrollment
16 participants
Primary outcome

Characterize the Maximum Plasma Concentration (Cmax) of PC14586 when co-administered with itraconazole in healthy participants.,Characterize the total drug exposure (AUC0-inf) of PC14586 when co-administered with itraconazole in healthy participants.,Characterize the time to peak drug concentration (Tmax) of PC14586 when co-administered with itraconazole in healthy participants.,Characterize the total drug exposure from time zero to 24 hours (AUC0-24) of PC14586 when co-administered with itraconazole in healthy participants.,Characterize the total drug exposure from time zero to the last timepoint (AUC0-t) of PC14586 when co-administered with itraconazole in healthy participants.,Characterize the half-life (t1/2) of PC14586 when co-administered with itraconazole in healthy participants.

Summary

The purpose of this study is to assess the effect of PC14586 pharmacokinetics when co
 administered with itraconazole in healthy participants.

ICD-10 classifications
Healthy person accompanying sick personRoutine general health check-up of armed forcesRoutine general health check-up of sports teamsRoutine general health check-up of inhabitants of institutions
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06362642
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06362642 through Pure Global AI's free database. This Phase 1 trial is sponsored by PMV Pharmaceuticals, Inc and is currently Recruiting. The study focuses on Healthy Volunteers. Target enrollment is 16 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.