Transcranial Alternating Current Stimulation in Cerebral Palsy (BOOSTTACS)

Assisting Hand Assessment (AHA),Box and Block Test (BBT),Visuomotor task

The present study aims to assess, through a randomized controlled trial (RCT), the efficacy
 of transcranial alternating current stimulation (tACS) in enhancing the functional changes
 due to an intensive motor training in children and adolescents with Cerebral Palsy (CP).
 Particularly, in two different groups active or sham tACS will be paired with the Hand-Arm
 Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) and we will assess the
 effects on the upper limbs motor ability and daily functioning in 6 to 17 years old patients
 with CP having mild-to moderate upper limb deficits. The investigators hypothesized that,
 thanks to the intensive bimanual training, both the active and the sham group will improve in
 motor functioning. However, in light of findings showing that tACS effectively improves motor
 learning, the investigators hypothesized that active tACS might improve in a greater and more
 lasting extent than sham tACS the motor functioning. Moreover, as suggested by previous
 studies investigating the effect of non-invasive brain stimulation (NIBS) in pediatric
 population, the investigators expected that the treatment will be safe and well tolerated.
 Such a result would encourage the use of NIBS to boost the rehabilitative training of motor
 abilities in children and adolescents with CP.