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NCT06381427Not yet recruiting

Perioperative Interdisciplinary, Intersectoral Process Optimization in Heart Failure

Perioperative Interdisciplinary, Intersectoral Process Optimization in Heart Failure: A Multicenter, Prospective-randomized Intervention Study
University of GiessenClinicalTrials.govother
Study focus
Disease/Condition
Heart Failure
Drug/Device/Intervention
Interdisciplinary decision-making for perioperative care
Study type
Interventional
Intervention type
other
Sponsor & location
Primary sponsor
University of Giessen
Location
Gießen, Germany
Timeline & enrollment
Phase
N/A
Start date
Sep 01, 2024
End date
Mar 01, 2027
Enrollment
1057 participants
Primary outcome

combined primary endpoint at 90 days post-operation : re-hospitalization,AKI, bacterial infection and cardiac decompensation

Summary

Chronic heart failure affects up to three million people in Germany, with prevalence
 increasing with age. It is a leading cause of cardiovascular disease-related deaths. Patients
 with heart failure undergoing non-cardiac surgery face higher risks of complications and
 death compared to those with coronary artery disease. Despite guidelines recommending
 comprehensive preoperative evaluation, there is no systematic risk assessment structure in
 place, leading to inadequate perioperative care. This study aims to evaluate a
 multidisciplinary approach for high-risk patients aged 65 and above, regardless of prior
 heart failure diagnosis, to mitigate postoperative complications. The investigators measure
 the NTpro BNP before surgery and include patients with NTproBNP 450 in this study and
 randomize them either to the standard care group or the intervention group.The hypothesis is
 that standardized risk screening and multidimensional care (Intervention group) can reduce
 complications in these patients undergoing non-cardiac surgery.

ICD-10 classifications
Heart failureHeart failure, unspecifiedCongestive heart failureHypertensive heart disease with (congestive) heart failureLeft ventricular failure
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06381427
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06381427 through Pure Global AI's free database. This phase not specified trial is sponsored by University of Giessen and is currently Not yet recruiting. The study focuses on Heart Failure. Target enrollment is 1057 participants.

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