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NCT06386627Completed

Study of Neurophysiological Markers of Motor Recovery in Post-stroke Patients.

Study of the Mechanisms of Visual-motor Transformation to Search for Neurophysiological Markers of Changes in the Functions of Cortical Motor Circuits in Patients With Neurological Disorders, and Development of Technologies for Their Rehabilitation.
Skolkovo Institute of Science and TechnologyClinicalTrials.govdiagnostic test
Verified
Study focus
Disease/Condition
Stroke
Drug/Device/Intervention
Stimulus response task
Study type
Observational
Intervention type
diagnostic test
Sponsor & location
Primary sponsor
Skolkovo Institute of Science and Technology
Location
Moscow, Russian Federation
Timeline & enrollment
Phase
N/A
Start date
Jul 01, 2023
End date
Mar 15, 2024
Enrollment
40 participants
Primary outcome

Atypical shape of lateralized readiness potential

Summary

The aim of the study was to explore potential pathways for recovery and adaptation of neural
 pathways after stroke by examining electrical activity of the brain cortex and cortico-spinal
 excitability using transcranial magnetic stimulation in people with motor impairment after
 stroke. Participants in the study performed a simple stimulus-response task with a healthy
 and a paralysed limb several times at different stages of basic rehabilitation. To compare
 the data, a group of healthy volunteers took part in a similar experiment. We recorded
 cortical activity using electroencephalography and muscle activity using electromyography.
 After the stimulus-response task, we also carried out a study using transcranial magnetic
 stimulation to assess the integrity of corticospinal connections.

ICD-10 classifications
Stroke, not specified as haemorrhage or infarctionSequelae of stroke, not specified as haemorrhage or infarctionCerebral infarctionFamily history of strokeCerebral infarction, unspecified
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06386627
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06386627 through Pure Global AI's free database. This phase not specified trial is sponsored by Skolkovo Institute of Science and Technology and is currently Completed. The study focuses on Stroke. Target enrollment is 40 participants.

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