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NCT06388486

Cytokine-Induced Transcription in Depressed Inpatients Undergoing Psychotherapy

University Medical Center Goettingen·ClinicalTrials.gov·behavioralCompleted
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Study focus
Disease/Condition
Depression
Drug/Device/Intervention
Psychotherapy
Study type
Observational
Intervention type
behavioral
Sponsor & location
Primary sponsor
University Medical Center Goettingen
Timeline & enrollment
Phase
N/A
Start date
Jan 01, 2017
End date
Jan 01, 2024
Enrollment
63 participants
Primary outcome

Change in depression

Summary

The goal of this observational study is to measure the levels of cytokine-induced
 transcription factor activation in a cohort of depressed inpatients undergoing psychotherapy.
 The study aims to answer the following main questions:
 
 - Do psychological traits (i.e.: social inhibition, negative affectivity, ...) affect the
 activation of immunomodulatory transcription factors (STAT3, NFkB) in depressed
 patients?
 
 - Are subjects with these psychological traits affected differently by psychotherapeutic
 intervention?
 
 Study subjects are assessed for their psychological and behavioral traits and receive
 psychotherapeutic care over several weeks during hospital treatment. Peripheral blood
 mononuclear cells are isolated from the study subjects, and activation of transcription
 factors is measured by flow cytometry.

ICD-10 classifications
Depressive episodeOther depressive episodesRecurrent depressive disorderRecurrent depressive disorder, unspecifiedPost-schizophrenic depression
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06388486
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06388486 through Pure Global AI's free database. This phase not specified trial is sponsored by University Medical Center Goettingen and is currently Completed. The study focuses on Depression. Target enrollment is 63 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.