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NCT06390631Recruiting

Effect of CPAP on Respiratory Load in COPD

Effect of CPAP on Respiratory Load and Lung Volume in Stable COPD
State Key Laboratory of Respiratory DiseaseClinicalTrials.govdeviceDevice trial
Verified
Study focus
Disease/Condition
Chronic Obstructive Pulmonary Disease
Drug/Device/Intervention
Continuous Positive Airway Pressure
Study type
Interventional
Intervention type
device
Sponsor & location
Primary sponsor
State Key Laboratory of Respiratory Disease
Location
Guangzhou, China
Timeline & enrollment
Phase
N/A
Start date
May 01, 2024
End date
Jul 10, 2024
Enrollment
19 participants
Primary outcome

Diaphragm EMG,Lung volume,Intrinsic positive end expiratory pressure (PEEPi),Inspiratory pressure,Inspiratory work,Sensation of breathing effort

Summary

Both intrinsic positive end expiratory pressure (PEEPi) and dynamic hyperinflation are
 considered as inspiratory loads which increase work of breathing in patients with COPD. The
 application of extrinsic positive end expiratory pressure (PEEPe) supplied by CPAP has been
 claimed to reduce inspiratory load based on change in esophageal pressure which could be
 significantly affected by change in lung volume and airflow. The investigator hypothesized
 that CPAP could increase respiratory load because it increases lung volume.

ICD-10 classifications
Other chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease, unspecifiedOther specified chronic obstructive pulmonary diseaseChronic obstructive pulmonary disease with acute exacerbation, unspecifiedChronic obstructive pulmonary disease with acute lower respiratory infection
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06390631
Type
Device Trial
About this record

Access comprehensive clinical trial information for NCT06390631 through Pure Global AI's free database. This phase not specified trial is sponsored by State Key Laboratory of Respiratory Disease and is currently Recruiting. The study focuses on Chronic Obstructive Pulmonary Disease. Target enrollment is 19 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.