NCT06405464

Cabotegravir Plus Rilpivirine Long-acting Regimen in the Swiss HIV Cohort Study:Uptake, Outcome, and Risk Factors for Treatment Failures

Name: Clinical Trial NCT06405464
Creator: University of Zurich
Keywords: HIV Infections, VOCABRIA 30Mg Tablet, drug, clinical trial, Switzerland

Cabotegravir Plus Rilpivirine Long-acting Regimen in the Swiss HIV Cohort Study: Uptake, Outcome, and Risk Factors for Treatment Failures in a Real-world Setting

University of Zurich·ClinicalTrials.gov·drugRecruiting

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Study focus

Disease/Condition: HIV Infections
Drug/Device/Intervention: VOCABRIA 30Mg Tablet
Study type: Observational
Intervention type: drug

Sponsor & location

Primary sponsor: University of Zurich
Location: Zurich, Switzerland

Timeline & enrollment

Phase: N/A
Start date: Mar 01, 2022
End date: Jun 30, 2026
Enrollment: 600 participants

Primary outcome

Proportion of individuals with viral blips,Proportion of individuals with confirmed viral failures,Proportion of individuals switching off CAB+RPV LA to previous or another oral regimen,Time to viral failure,Proportion of participants who discontinue treatment due to drug-related reasons,Proportion of participants who discontinue treatment due to drug-unrelated reasons,Proportion of participants by characteristics,Overall adherence to Swiss label indication in CAB+RPV LA prescriptions,Overall adherence to the proposed injection schedules,Proportion of participants by treatment adherence category

Summary

This study aims to characterize Swiss HIV Cohort Study participants initiating the CAB+RPV LA regimen, assess adherence to Swiss label indications, and describe treatment outcomes in this large, multicentre, heterogeneous, high-income setting. Moreover, the study aims to assess virological, immunological, demographic, clinical, and behavioural factors associated with viral failure under CAB+RPV LA regimen.

ICD-10 classifications

HIV disease resulting in other viral infectionsHIV disease resulting in other bacterial infectionsHIV disease resulting in multiple infectionsAcute HIV infection syndromeHIV disease resulting in other infectious and parasitic diseases

Data source

Registry: ClinicalTrials.gov
Trial ID: NCT06405464
Type: Non-Device Trial

About this record

Access comprehensive clinical trial information for NCT06405464 through Pure Global AI's free database. This phase not specified trial is sponsored by University of Zurich and is currently Recruiting. The study focuses on HIV Infections. Target enrollment is 600 participants.

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