A Study of TQC3927 Powder for Inhalation in Healthy Adult Subjects
- Disease/Condition
- Chronic Obstructive Pulmonary Disease
- Drug/Device/Intervention
- TQC3927 powder for inhalation
- Study type
- Interventional
- Intervention type
- drug
- Primary sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
- Location
- Beijing, China
- Phase
- Phase 1
- Start date
- May 01, 2024
- End date
- Feb 01, 2025
- Enrollment
- 60 participants
Adverse events (AE),Serious adverse events (SAE),Abnormal security check,Pharmacokinetics:Peak concentration (Cmax),Area Under the Concentration-Time Curve From 0 to Last Observation (AUC [0-t]),Area Under the Concentration-Time Curve From Zero to Infinity (AUC [0-infinity]),Time to reach maximum (peak) plasma concentration following drug administration (Tmax),Half-life (t1/2),Apparent volume of distribution(Vd/F),Apparent clearance (CLz/F),End elimination rate (λz),Residual area percentage of the TQC3927 (AUC_%Extrap),Mean residence time from zero to last measurable concentration (MRT0-t),Mean residence time from zero to infinity (MRT0-∞),Accumulated excretion of drugs in urine and feces (Aecum),Accumulated excretion of drugs in urine (Aeu,cum),Accumulated excretion of drugs in feces(Aef,cum),Renal clearance (CLr),Total drug excretion ratio in urine and feces (Fe%),Drug excretion ratio in urine (Fe%u),Drug excretion ratio in feces (Fe%f)
This is a dose escalation trial. The dosing regimen involves a single-dose study. This is a
 single-center, randomized, double-blind, placebo-controlled study to evaluate the safety,
 tolerability and pharmacokinetic characteristics of TQC3927 powder for inhalation in healthy
 adults subjects.
- Registry
- ClinicalTrials.gov
- Trial ID
- NCT06408285
- Type
- Non-Device Trial
Access comprehensive clinical trial information for NCT06408285 through Pure Global AI's free database. This Phase 1 trial is sponsored by Chia Tai Tianqing Pharmaceutical Group Co., Ltd. and is currently Not yet recruiting. The study focuses on Chronic Obstructive Pulmonary Disease. Target enrollment is 60 participants.
This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.