NCT06408688

Safety and Modulation of Adaptive Immunity by Iscador® Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors

Safety and Modulation of Adaptive Immunity by Iscador® Qu Viscum Album Extract in Patients With Advanced, Recurrent or Metastatic Cancers Treated With Immune Checkpoint Inhibitors - a Randomized Trial
University Hospital, Basel, Switzerland·Phase 4·ClinicalTrials.gov·drugNot yet recruiting
View on ClinicalTrials.gov
Study focus
Disease/Condition
Advanced Solid Tumor
Drug/Device/Intervention
Immune checkpoint inhibitors plus Iscador® Qu.
Study type
Interventional
Intervention type
drug
Sponsor & location
Primary sponsor
University Hospital, Basel, Switzerland
Location
Baden,Basel,Liestal,Saint Gallen, Switzerland
Timeline & enrollment
Phase
Phase 4
Start date
Jun 01, 2024
End date
Nov 01, 2026
Enrollment
100 participants
Primary outcome

Percentage of patients with a relative increase in T cell richness or diversity of 20% or more,Percentage of patients with a relative decrease in T cell clonality of 20% or more,Level of T cell richness,Level of T cell diversity,Level of T cell clonality

Summary

The main objective of this study is to test if adding the mistletoe extract Iscador® Qu to
 regular cancer treatment with immune checkpoint inhibitors affects:
 
 - The immune system's ability to fight cancer
 
 - Safety of the treatment
 
 - How well the treatment performs against cancer
 
 - How the patient feels during treatment
 
 Researchers will compare patients treated with immune checkpoint inhibitors plus Iscador® Qu
 with patients treated with imune checkpoint inhibitors only.

ICD-10 classifications
Carcinoma in situ, unspecifiedMalignant neoplasm: PrepuceMalignant neoplasm: Connective and soft tissue, unspecifiedMalignant neoplasm: ParametriumMalignant neoplasm of other connective and soft tissue
Data source
Registry
ClinicalTrials.gov
Trial ID
NCT06408688
Type
Non-Device Trial
About this record

Access comprehensive clinical trial information for NCT06408688 through Pure Global AI's free database. This Phase 4 trial is sponsored by University Hospital, Basel, Switzerland and is currently Not yet recruiting. The study focuses on Advanced Solid Tumor. Target enrollment is 100 participants.

This page provides complete trial specifications, intervention details, outcomes, and location information. Pure Global AI offers free access to ClinicalTrials.gov data, helping medical device and pharmaceutical companies navigate clinical research efficiently.